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10.1073/pnas.1817473116 175 ShelineC

The activation or upregulation of the Nrf2 level leads to cytoprotection under stress conditions through various mechanisms, including the removal of ROS and oxidative stress, as well as anti-inflammatory and anti-apoptosis mechanisms

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In our study, we found that the genes associated with mitophagy and recruitment of genes involved in pathways which typically compensate for physiological stress, such as DRP1, are upregulated with increased BT concentrations

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Propofol Propofol administered intravenously is commonly used for induction and short duration anesthesia in dogs and humans