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Initial Treatment: For severe cases, doses can be 1000 mcg to 2000 mcg

Transdermal Delivery Transdermal skincare patches are designed to deliver active ingredients directly into the skin over an extended period, providing continuous, targeted treatment

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doi:10.1053/j.gastro.2012.09.007 [2] Buchman AL, Katz S, Fang JC, Bernstein CN, Abou-Assi SG

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Roulston, A., Marcellus, R