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Jama 1999, 282 (17), 16591664

In conclusion, enzymatic antioxidants typically serve as components of complicated enzymatic systems that detoxify ROS and regenerate other antioxidants, whereas nonenzymatic antioxidants are smaller molecules capable of directly neutralizing free radicals
These findings suggest that exercise training can effectively stimulate the antioxidant pathway, mitigate apoptosis, reduce myocardial fibrosis in a manner dependent on the intensity, type, or duration of exercise
Sgouras et al

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