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Stress reduction through meditation, yoga, or other practices reduces baseline inflammation

In epilepsy, this interplay is evident in models such as the lithium-pilocarpine (Li-Pilo) model of SE, which recapitulates key features of epileptogenesis including altered glucose metabolism (Dank et al., 2022) and mitochondrial bioenergetics with increased markers of oxidative damage (Carrasco-Pozo et al., 2015

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[DOI] [PMC free article] [PubMed] [Google Scholar] 40.Chen T.H., Murata N

Other cellular components contribute too

PIP3 recruits and activates Akt (also called protein kinase B), a master regulatory kinase that phosphorylates dozens of downstream substrates to promote anabolism and cell survival