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Thus, since otherwise inescapable somatoneuron depletion following a capsaicin application could completely be avoided with a daily NaBPC157 application, it is possible that the effects of NaBPC157 could be related specifically to the integrity of capsaicin sensitive somatosensory neurons and their protection (i.e., primary afferent neurons having small diameter somata and unmyelinated (C-) or thinly myelinated (A-8) fibers)

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Requires careful evaluation are adults with active or historical cancer (growth-promoting compounds require oncology-history review), significant cardiovascular disease, multiple medications requiring interaction screening, or pituitary conditions for growth hormone secretagogues

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