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Upon binding to cytoplasmic glucocorticoid receptors (GR), corticosteroids induce translocation of GR complexes into the nucleus, where they interact with glucocorticoid response elements (GREs) to upregulate anti-inflammatory genes (e.g., IL-10, DUSP-1) and suppress pro-inflammatory mediators like IL-1, IL-6, TNF-, and chemokines, such as MCP-1 and IL-8 (McManus 2003

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A J code is a category of HCPCS Level II codes used to identify injectable drugs, chemotherapy agents, and other non-oral medications administered in clinical settings

Less delayed-onset muscle soreness, faster return to baseline strength between hard workouts, and reduced stiffness in nagging joints

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CagriSema's NDA was filed with FDA in December 2025