ipamorelin 5 days on 2 days off protocol CJC-1295 (NO DAC) + – Research Peptide CJC-1295 no-DAC + Ipamorelin: What
Description
Whether repeated ipamorelin dosing leads to tachyphylaxis (reduced response over time) has not been systematically studied in long-term protocols

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Acid suppression medications and metformin also reduce vitamin B12 absorption and so increase the risk of deficiency

Gaskell H, Moore RA, Derry S et al

The World Anti-Doping Agency (WADA) classifies all growth hormone secretagogues, GHRH analogs (including both CJC-1295 variants), and GHRPs under Section S2 of the Prohibited List

PLoS One 7 , e40195 (2012)
