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To further characterize the feature of new OL genesis during whole course of this model, we further took the advantage of our recently identified OL lineage cell stage-specific marker, ENPP6, a choline-specific ecto-nucleotide pyrophosphatase /phosphodiesterase (ENPP), which is highly expressed in newly-forming/formed OLs and at a much lower levels in these more mature/old (earlier-formed) myelinating OLs (to the extent that the ISH signal would easily disappear if the development time were shortened), but not at all in OPCs, neurons, astrocytes or vascular endothelial cells (Xiao et al., 2016

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Get enough through food or supplementation if you need it, especially if you are vegan, older or have a condition that affects absorption

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[DOI] [PMC free article] [PubMed] [Google Scholar] 95.Matheis F, Muller PA, Graves CL, Gabanyi I, Kerner ZJ, Costa-Borges D, et al
