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Effects of cigarette smoke and a heterocyclic amine, MeIQx on cytochrome P-450, mutagenic activation of various carcinogens and glucuronidation in rat liver

However, it is not recommended to combine it directly with high concentrations of vitamin C (L-ascorbic acid) or AHAs, as the acidic pH of these actives can destabilize the copper complex and reduce GHK-Cu efficacy
doi: 10.1038/351122a0
So surface area matters

[DOI] [PMC free article] [PubMed] [Google Scholar] 58.Sies H

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