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The complete sequence of this research compound is: Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe, with a disulphide bond between the two cysteine residues (Cys-7 and Cys-15) that contributes significantly to the structural stability of the peptide loop conformation

Treatment of Drosophila flies with kynurenine pathway inhibitors and the NAD + precursors NR or NAM increased the lifespan of these animals, suggesting an advantage in combining different therapeutic strategies

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