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Aif3 splicing variant elicits mitochondrial malfunction via the concurrent dysregulation of electron transport chain and glutathione-redox homeostasis

Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

[DOI] [PMC free article] [PubMed] [Google Scholar] 18.Rejali L., Ozumerzifon S., Nayeri H., Asgary S

4 Conclusion and perspectives This review synthesizes the current knowledge on the impact and potential mechanisms of exercise and physical activity on common ocular diseases such as DED, cataracts, myopia, glaucoma, DR, and AMD, as depicted in Figures 26

A possible hypothesis is that, as GSH is a substrate of GSH-Px, high GSH levels could be a consequence of the increase in oxidative stress induced by a reduction of GSH-Px activity