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Dalton, T
The ability of proliferation was assessed by a Cell Counting Kit-8 (CCK-8, Dojindo, Rockville, MD, United States) at different time points post-plating
Cell-culture (3T3-L1 adipocytes) 5-Amino-1MQ at 30 M strongly reduced 1-MNA levels in mouse fat cells, confirming NNMT inhibition (Neelakantan et al., Biochemical Pharmacology, 2018)
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In order to explore whether YTHDF1 expression level impacts chemotherapy tolerance of MRTK cells, we treated YTHDF1 KO and vector control cells with doxorubicin at different concentrations (0.1, 0.25 and 0.5 M)
