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HTS led to the identification of small molecules including VX-325 (C3) and corr-4a (C4) that rescue the folding defect of F508del-CFTR (correctors) 57 (Box 2)

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[PMC free article] [PubMed] [Google Scholar] Zhang C., Wang J., Ma X., Wang W., Zhao B., Chen Y., et al

These findings indicate that CD39 is a biomarker of conventional CD4+ T cells, with both depletion and cytotoxic potential

These findings suggest that the repair function of PT in early DKD could be caused by a decrease in proliferative PT cells

This high selectivity enables quantification within complex biological matrices with minimal sample fractionation