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doi: 10.1074/jbc.M002915200

doi: 10.4161/cam.20631
Macrocyclic lactone Rapamycin, a macrocyclic lactone isolated from Streptomyces hygroscopicus , is known for its immunosuppressive and antimicrobial properties due to its ability to inhibit the mTOR pathway, thereby promoting autophagy [63]

[DOI] [PubMed] [Google Scholar] 41.Zhou X., He L., Zuo S., Zhang Y., Wan D., Long C., Huang P., Wu X., Wu C., Liu G., et al

10.1016/j.biopha.2011.04.020 43 JiaP.XuY
We must note that in the present work, we focused on a specific EV population of resting neutrophils that has been previously characterized and functionally tested in various in vitro scenarios, showing anti-inflammatory effects