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Branched chain amino acids-alpha-ketoglutarate transaminase

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[77] compared the metabolic profile of CD patients intestinal mucosa (relative to the disease controls), blood plasma, and urine (relative to the healthy controls) samples using NMR spectroscopy and multivariate analysis and observed the changes in Pro, arginine (Arg), glycine (Gly), histidine (His), glutamate (Glu), aspartate (Asp), tryptophan (Trp), fumarate, formate, succinate (Succ), glycerophosphocholine (GPC) and allantoin (Alln) in the small intestinal mucosa and changes in Pro, Arg, Gly, alanine, Glu, Gln, glucose (Glc), lactate (Lac), acetate (Ace), acetoacetate (AcAc), -hydroxybutyrate (-OHB), pyruvate (Pyr), Succ, citrate (Cit), choline (Cho), creatine (Cr), phosphocreatine (PCr) and creatinine in blood plasma and changes in Pro, Trp, -OHB, Pyr, Succ, N-methylnicotinamide (NMN), aminohippurate (AHA), indoxyl sulfate (IS), and Alln in urine samples of CD patients [77]

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Severe valproate induced hyperammonemic encephalopathy successfully managed with peritoneal dialysis

Understanding these nuances is essential for patients seeking to address the specific systemic deficits caused by complex chronic illnesses