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Reau, MD Improvements in MASH-related noninvasive test parameters were also observed across body weight reduction thresholds in patients receiving semaglutide, as were improvements in fibrosis-related histologic and noninvasive test responses, including change in ELF scores and VCTE

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Those with family histories of certain thyroid and endocrine disorders should avoid this treatment

Practical hydration targets: Baseline: 2 to 3 liters of total fluid daily (including from food) After each vomiting episode: add 250 mL of an electrolyte solution (ORS packets, Pedialyte, or a homemade mix of 1 liter water + 6 teaspoons sugar + teaspoon salt) Signs you are behind: dark yellow urine, dry mouth, dizziness when standing, reduced urine frequency Fluids to prefer: water, diluted broths, herbal teas (peppermint or ginger), electrolyte drinks without artificial sweeteners (sugar alcohols like sorbitol can worsen GI symptoms on GLP-1 agonists)
