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First described in 2015, MOTS-c is unusual because it is encoded by mitochondrial DNA rather than nuclear DNA

Findings imply that TB-500, through modulation of actin and cellular migration, may assist in reorganizing provisional matrix scaffolds

Therefore, it is unclear whether many of the observed phenotypes are a direct consequence of inhibition of the TCA cycle or the respiratory chain

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In addition, they show antifungal activity against Aspergillus flavus , A niger , and A fumigatus , and yeasts such as Rhodotorula mucilaginous , Candida krusi , C glabrata , and C albicans (100, 125)