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Description
G6PD-deficient endothelial cells show reduced expression of endothelial NO synthase and decreased NO levels along with a reduction in GSH [11]

KumarVSinhaAKRomanoNAllenKMBowmanBAThompsonKRet al

The HO-1 system is amenable for use in the development of new therapies, some of them currently under experimental and clinical trials
However, neurodegenerative disease mechanisms differ substantially between animal models and human diseases, and premature clinical use based solely on animal data could expose patients to unknown risks without established benefits
15 (1), 015001 (2019) A.M

& Tapsell, L
