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For the older patients (60+ years) specially with arteriosclerosis, possibility of circulatory collapse after administration should be kept in mind (30)

Moreover, BAC systems contribute to the removal of pathogens in potable water, achieving regulatory goals for log removal of microorganisms

PMID 19832808

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The drug can cause severe dehydration, overheating, heart complications, and, in some cases, life-threatening medical emergencies

Metformin--mode of action and clinical implications for diabetes and cancer