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For instance, we recently showed that remifentanil, a MOR selective agonist, produces a significant desensitization by 60% on the cAMP pathway after 10 min while at the same time desensitization of the MAP kinases ERK1/2 signaling pathway was not significantly affected (Nowoczyn et al., 2013)

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Adipose tissue heterogeneity: Implication of depot differences in adipose tissue for obesity complications

Oxidative stress from alcohol in the brain

Ndufs2 fx/fx ) mice at 3 months of age on a chow diet (n = 2)

AC could dramatically reduce ROS production, downregulate caspase-3 and Bax expression, and upregulate Bcl-2 expression