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Ensifentrine (RPL554): an investigational PDE3/4 inhibitor for the treatment of COPD

Many of these uses remain investigational for otherwise healthy individuals

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For this, 10 M wild type SnCE1 and inactive mutant C256A were incubated with 0.05 mM and 1 mM of acetyl group donor acetyl-CoA (Cayman Chemicals, cat no

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