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Description
Monitoring by a healthcare provider is key

Structure-based identification and biological characterization of new NAPRT inhibitors

A pharmacokinetic study in rats found that oral administration produced substantial plasma concentrations, with a maximum concentration of 2252 ng/mL and an elimination half-life of approximately 6.9 hours

[PubMed: 11684884] 112

Other causes are conditions affecting the stomach or small intestine, such as Crohns disease, operations such as gastrostomies (which involve removal of part of the stomach), and certain medications

Rodents have higher metabolic rates relative to body mass, different adipose tissue distribution, and a brown fat compartment that is more metabolically active
