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Two open label studies tested the effect of ALC in patients with neuropathy induced by paclitaxel and cisplatin

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49 Statin affects the expression of PXR-targeted genes SLCO1b2 (solute carrier organic anion transporter family, member 1b2), which encodes the major glucose transporter of the hepatocytes, and CYP3A11 (cytochrome P450, family 3, subfamily a, polypeptide 11), to be increased in atorvastatin-treated mice
