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Diabetic patients who were on statin therapy had lower MTP mRNA compared to those not on statins [81]

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Injection site reactions and gastrointestinal symptoms were common adverse events (AEs)

These initial experiments were unsuccessful, likely due to the low expression levels of Ozz and Alix in steady-state mitochondria

47 Emerging evidence has unveiled lactate as a pleiotropic molecule functioning beyond mere metabolic waste, serving as an energy substrate, redox buffer, fatty acid metabolism modulator, immunometabolic regulator, and intercellular signaling mediator