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Oxidative stress as a therapeutic target in amyotrophic lateral sclerosis: opportunities and limitations

Furthermore, severe prenatal-onset SMA type I cases reveal pronounced cortical involvement in the disease process, with degenerative changes in layer V of the M1 characterized by chromatolytic ballooned neurons and neuronophagia [12]
Studies have shown that Prmt4 is overexpressed in a variety of tumors, including breast cancer, prostate cancer and colorectal cancer (162164)

doi: 10.3390/cells8040327 97

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Accordingly, Calabrese et al
