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These synthetic peptides differ in amino acid sequence and biologic properties.I3 In our previous studies, we demonstrated that injection of thymosin a', thymopentin, or THF-y2 into aging mice can increase T-cell functions when spleen cells were tested in vitro for T helper cell activity, proliferative responses to T-cell mitogens, cytokine production, and expression of cytokine receptors

The rationale for their use in BH 4 Ds is the presence of symptoms attributable to serotonin deficiency such as psychiatric and behavioural disorders and sleep problems

doi: 10.1016/j.beem.2021.101493 108 LiN.ChenH.ChengY.XuF.RuanG.YingS.et al

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Minipuberty is an essential diagnostic window for evaluating the functional integrity of the HPG axis in conditions like Congenital Hypogonadotropic Hypogonadism (CHH) and Disorders of Sex Development (DSDs) [18, 20, 21]