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Since venetoclax and AZD-5991 rapidly induce apoptosis in CLL cells, these compounds were added in the last 24 hours of incubation to minimize single-drug cytotoxicity

After transferring the methyl group, SAM is converted to S-adenosylhomocysteine (SAH) and hydrolyzed into adenosine and homocysteine

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10.7554/eLife.56580 78 JeongS

As evaluated, pFeSAN exhibited a long-term stability in water, acetate buffer (pH 4.0) and cell culture medium without the significant changes of the average hydrodynamic diameters during 1-week co-incubation (Supplementary Fig

It is a central non-enzymatic antioxidant in sperm cells that exists in reduced (GSH) and oxidized (GSSG) forms, cycling between the two via the glutathione peroxidase/reductase system, with support from NADPH