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Always consult your healthcare provider before discontinuing therapy, as abrupt cessation can trigger hunger signals and unplanned weight gain within weeks
GLP-1 Receptor Agonism GLP-1 is primarily synthesised in the intestinal endocrine L-cells with the highest density in the distal ileum

Tirzepatide Tirzepatide, similar to semaglutide, is administered via a weekly injection

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The Bottom Line May 2026 Status Editorial note: This article is a news update covering FDA regulatory action as of May 2026

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