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The subsequent Fenton reaction between Cu + and H 2 O 2 , along with the reaction between Cu + and H 2 O 2 , creates a cyclic catalytic process that produces large amounts of ROS, triggering an intracellular ROS storm

At day 6 after the first infusion, the semaglutide-treated and GLP-1MK-801-treated mice were crossed-over in terms of treatment and administered with another single infusion of either GLP-1MK-801 (0.22 nmol, 2 l) and semaglutide (0.22 nmol, 2 l), respectively, while vehicle-treated mice received vehicle treatment once again