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The substratereceptor complex is internalized by endosomes via the clathrin-dependent pathway, followed by lysosomal hydrolysis, where the lipid is dissociated from the complex due to a low pH, and the receptor is recycled back to the cell surface [156,157]

T allele carriers (i.e

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The acetyl group keeps the molecule intact, allowing it to be absorbed through the intestine and converted back into active glutathione intracellularly