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In a subsequent joint report, the WHO and FAO emphasized that the no observed adverse effect level (NOAEL) established for histamine was only valid for healthy people, and not for members of susceptible populations, such as those with histamine intolerance [30]

Accumulation of the toxic metabolite can then exert untoward effects on key cellular structures and functions (Figure 1)

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Mikus D, Sikiric P, Seiwerth S, Petricevic A, Aralica G, Druzijancic N, et al

Methionine is activated to S-adenosylmethionine (SAM) by the enzyme methionine adenosyltransferase

Fahn S (1992) A pilot trial of high-dose alpha-tocopherol and ascorbate in early Parkinsons disease
