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Description
Serious Indicators of Vitamin B-12 Deficiency Severe vitamin B12 deficiency can cause signs and symptoms such as Yellow skin Weak muscles Numb or tingly hands or feet Trouble walking Severe joint pain Increasing shortness of breath Weight loss Irritability Lack of smell and taste sensations Memory loss Paranoia Delusions Deep depression What Does B12 Fatigue Feel Like

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A corresponding moderate increase in the functional metabolic biomarkers plasma methymalonic acid and homocysteine suggests that some depletion of maternal intracellular vitamin B12 has occurred even though serum B12 concentrations are high (Varsi et al., 2018)

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Hypokalemia and thrombocytosis could occur upon conversion of severe megaloblastic to normal erythropoiesis with B12 therapy
