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10.1038/nchembio.2079 119 SiregarA
Simon 1998
Chronic Inflammation and Cataracts Chronic inflammation may develop as a result of chronic poor dietary and lifestyle habits, too much stress, and chemical exposure
8095, 1978, pp
it is not, on its own, evidence sufficient to support a claim of life extension in humans absent independent randomized trials
In synovial fibroblasts, proinflammatory cues directly impair methylation capacity: IL-1 rapidly downregulates DNMT1 and DNMT3A/3B expression and activity, promoting demethylation and stable activation of inflammatory gene programs (116)
