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The GPX family encompasses eight members, designated as GPX1-8, which collectively contribute to inhibiting oxidative stress and maintaining redox equilibrium [46]

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For example, the inhalant and oral solution forms have a mucolytic effect, and are used to relieve obstructions in bronchial diseases and in tracheotomy procedures

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Originally native to Southern Europe, the Mediterranean region, Western Asia and North Africa, Silybum marianum is today found worldwide including in North and South America and Southern Australia

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