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The role of homocysteine in increasing the risk of hemolysis in vitamin B12 and folate deficiency has been demonstrated in vitro .[7] We postulate that the high homocysteine levels in our case may have played a role in ensuing hemolysis in addition to intramedullary destruction of RBCs
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Wang K, Yuan A, Yu J, et al
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doi: 10.1073/pnas.87.18.7185
PilZ domain proteins bind cyclic diguanylate and regulate diverse processes in Vibrio cholerae
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Vijay S, Patterson A, Olpin S, Henderson MJ, Clark S, Day C et al