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Strict sun avoidance beginning in infancy, use of protective clothing, and close clinical monitoring of the skin are key components to management of XP

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PMID 2435144

under the brand name Scenesse, an implantable form of afamelanotide has been approved in the EU, US, and elsewhere to reduce phototoxicity in erythropoietic protoporphyria (EPP)

Cells expressing the G175S mutant PMEL exhibited approximately twofold higher levels of intracellular amyloids compared to wild-type PMEL-expressing cells, consistent with enhanced amyloidogenic efficiency

He and his wife, Keli, have a sort of his-and-hers practice: she co-founded a wellness spa next door