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Future studies of the compound should use male mice to confirm that its effects are not sex-specific

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As previously mentioned, NRF2 plays a crucial role in regulating various antioxidant enzymes that neutralize harmful reactive oxidants and electrophiles, converting them into less harmful forms (Table 1)

These challenges have led to the development of more stable analogues, improved delivery systems, and increased interest in smaller peptide fragments that retain bioactivity while minimizing these drawbacks [9]

1 Introduction Cisplatin is one of the most effective and widely used anticancer drugs