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10.1016/j.bmcl.2016.01.076 107 SunY.JingX.MaX.FengY.HuH

E.Rivera-MezaM.Berrios-CarcamoP.CasselsB

Liao et al., 2014

As phase II detoxification enzymes, arthropod GSTs confer pesticide resistance through direct metabolism or sequestration of pesticides and indirectly by providing protection against oxidative stress induced by synthetic pesticides [22]

One of the earliest biochemical changes seen in PD is a decrease in the levels of total GSH which occurs even before a reduction in mitochondrial complex 1 activity, dopamine levels, or the neurodegeneration that are all associated with the disease (Chinta et al., 2007)

Glutathione (CAS number 70-18-8) represents an endogenous tripeptide compound with the molecular formula C10H17N3O6S and molecular weight of 307.32 g/mol