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Efficacy and safety of oral semaglutide with flexible dose adjustment versus sitagliptin in type 2 diabetes (PIONEER 7): a multicentre, open-label, randomised, phase 3a trial
A possible explanation for the similar effects on weight of both GIP agonism and antagonism is the potential desensitisation of GIP receptors by GIP agonists exposure [57]

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Raschi E, Fusaroli M, Ardizzoni A, Poluzzi E, De Ponti F

This raises the possibility that GLP-1 agonists could be used in combination with existing treatments for OUD to improve outcomes for individuals trying to quit opioid use

2020;21(6):p
