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We evaluated the prognostic value of TMAO among hospitalized patients at nutritional risk participating in the Effect of early nutritional support on Frailty, Functional Outcomes, and Recovery of malnourished medical inpatients Trial (EFFORT) regarding clinical outcomes and response to nutritional support

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Abbreviations IEM: Inborn error of metabolism mFAO: Mitochondrial fatty acid -oxidation CASTOR: Coenzyme A sequestration, toxicity and redistribution CoASH: Free coenzyme A MCAD: Medium-chain acyl-CoA dehydrogenase MCADD: MCAD deficiency ED: Early diagnosis CPT1: Carnitine palmitoyltransferase 1 CPT2: Carnitine palmitoyltransferase 2 CACT: Carnitine acylcarnitine translocase VLCAD: Very-long-chain acyl-CoA dehydrogenase SCAD: Short-chain acyl-CoA dehydrogenase ACAD: Acyl-CoA dehydrogenase CROT: Crotonase M/SCHAD: Medium-/short-chain hydroxyacyl-CoA dehydrogenase MCKAT: Medium-chain ketoacyl-CoA thiolase MTP: Mitochondrial trifunctional protein ACOTcs: Acyl-CoA thioesterase (CoA-sensitive) ACOTcs: Acyl-CoA thioesterase (CoA-insensitive) ETF: Electron-transferring flavoprotein References Ferreira CR, Rahman S, Keller M, Zschocke J