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Thus, ferroptosis induction may be one mechanism by which periodontitis increases the severity of T2DM
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& Blackstone, C
Liu et al., 2022), NF-B activation may lead to the upregulation of genes encoding antioxidative enzymes such as SOD2 and GPX4 (Liu et al., 2022)
However, there is an interdependent relationship in which the NADPH pool is simultaneously supported and used by various pathways in cells
