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The monomers, with molecular weights of 7080 kDa, are composed of three domains: (i) an N-terminal domain, (ii) a central -helical domain containing the active site-binding copper ions, and (iii) a C-terminal domain with a -sheet structure

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Pseudotyped E1E2 lysates from transfected 293Tcells (described above) were quantified for total protein using a Bradford assay

A study on three lupus nephritis patients demonstrated that anti-mCRP antibodies purified from IgG fractions by affinity chromatography could significantly inhibit the binding of mCRP with C1q or factor H, and eliminate late apoptotic cell clearance enhanced by mCRP, suggesting that anti-mCRP antibodies from lupus nephritis patients might be pathogenic in SLE and lupus nephritis via interfering with the biofunctions of mCRP [165]

doi: 10.1111/bjd.14355 [DOI] [PubMed] [Google Scholar] 50.Micantonio T, Neri L, Longo C, et al

Triggered by multiple environmental factors and genetic predisposition, IR paves the way for several related diseases, including metabolic associated diseases, cardiovascular diseases and cancer