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A terminal disclaimer is a legal statement filed with the USPTO in which a patent applicant agrees to limit the term of a later-filed patent so it expires no later than an earlier related patent, often in the same patent family

Compounded drugs can be important for overcoming shortages or meeting unique patient needs but compounders should not try to compound drugs in a way that circumvents FDAs approval process. The 30 companies that received warning letters are mostly small to midsize, digital telehealth providers that moved quickly to meet surging consumer demand for GLP-1 weight loss therapies when manufacturing capacity constraints limited supplies

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Development of oral, depot, or transdermal delivery systems may improve adherence

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