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This conjugation neutralizes the toxins and transforms them into highly water-soluble compounds

Deficiency can occur in certain populations, including older adults, vegans, individuals with pernicious anaemia, those with malabsorption disorders such as Crohn's disease or coeliac disease, people who have had bariatric surgery or gastrectomy, and those on long-term medication such as metformin or acid-suppressing drugs

Peroxiredoxin (Prx) 3, a cysteine-dependent peroxidase enzyme, is also present in the mitochondria, whereas Prx5 can also be found in the cytosol, in peroxisomes, and in the nucleus [28]

This recycling process occurs constantly in healthy and transformed cells and is orchestrated by proteasomes and aminopeptidases (Saric et al

A., Maroney, M