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Serious adverse effects are rare, and most people tolerate B12 supplementation well

This vitamin b12 deficiency skin problems tend to cause darkening of the skin, patchy, especially on the hands, feet, and joints

An unplanned 3-day gap during a loading phase is equivalent to an extended weekend break

INTRODUCTION Obesity has progressed to epidemic proportions globally, with more than 1.6 billion adults overweight and at least 400 million of them clinically obese [1]

Overall, there is not sufficient evidence to recommend B12 on its own for the elderly with impaired cognitive function, although those with early symptoms may benefit