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FMO3 encodes an enzyme in the liver that converts trimethylamine (TMA)made by gut bacteria after you eat certain foodsinto trimethylamine-N-oxide (TMAO), which is easier for your body to eliminate

Conversely, according to the 2024 expert consensus [41], the share of energy from carbohydrates is less than 10%, which in practice corresponds to 2050 g of carbohydrates per day - this is because higher carbohydrate intake requires higher insulin production, which inhibits ketogenesis, as previously mentioned

10.18632/aging.102352 26 GaoX.LiuX.XuJ.XueC.XueY.WangY

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For instance, it promotes macrophage polarization (87), resulting in a 50% increase in M2-type macrophages and a 50% decrease in M1-type macrophages (88)

Research indicates that gut microbes and the metabolites they produce play a crucial role in regulating inflammation, neurotransmitter production and stress pathways that impact mood and cognitive processes