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The sub-threshold doses of HGF and Dihexa combined, however, appeared to produce an effect similar to the saturating doses of HGF and Dihexa (p 0.05 by one-way ANOVA followed by Tukey post hoc test) as shown in Figure 20

Figure S4

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Physicochemical properties of metal-based nanoparticles that influence toxicity The physical and chemical properties of NPs act as key factors affecting NP uptake, translocation and accumulation in live tissues, which determines the fate of NPs and their mechanisms of toxicity (Zoroddu et al., 2014)

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