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These LC neurons receive projections from pre-proglucagon expressing neurons, indicating a possible role in the physiologic control of food intake by the endogenous GLP-1 system

GLP-1 medications entered this conversation because they do more than reduce appetite for some patients

CNS glucagon-like peptide-1 receptors mediate endocrine and anxiety responses to interoceptive and psychogenic stressors

Healthcare facility capacity development in obesity management creates infrastructure for comprehensive patient care delivery

80% of patients at that point were still on the drug, a self-described impressive retention rate suggesting very good tolerability

Furthermore, emerging studies provide evidence that SGLT2-i might have an interfering effect on aldosterone/renin ratio (ARR) in patients with T2DM, due to their diuretic and sympathoinhibition effects