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The collagen story is really a remodeling story The first clean fibroblast result landed in 1988, when Maquart and colleagues reported in FEBS Letters that GHK-Cu pushed cultured skin fibroblasts to make more collagen at concentrations as low as 10 M

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Dubnau, E., Chan, J., Mohan, V.P

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J Mol Med (Berl) 95:323333 Hsieh MJ, Lee CH, Chueh HY, Chang GJ, Huang HY, Lin Y et al (2020) Modulatory effects of BPC 157 on vasomotor tone and the activation of Src-Caveolin-1-endothelial nitric oxide synthase pathway