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ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions

As L-carnitine has diverse biological activities, additional studies will be required to determine whether its beneficial effects are attributable to its antioxidant properties

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Additionally, iNOS is among the central downstream genes of NF-B, but, in turn, iNOS can promote and inhibit NF-B activity (142)

Alotaibi AA, Yilmaz M, Kadia T, DiNardo C, Borthakur G, Guerra V, Andreeff M , Konopleva M, Pemmaraju N, Jabbour E, Short N, Garcia-Manero G, Patel K, Ravandi-Kashani F, Kantarjian H, Daver N